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Human MASP3 (450-721) Protein, His Tag (active enzyme)

Human MASP3 (450-721), His Tag (MA3-H52H3) is expressed from human 293 cells (HEK293) . It contains AA Ile 450 - Val 721 (Accession # P48740-2) .

Product Specifications

Background

MASP3 is a member of the MASP family. The MASP family proteins were first discovered as complexes with mannose-binding lectin (MBL) and therefore named MBL-associated serine proteases, but later, they were found to interact with ficolins, and later still, collectin-10 and collectin-11. As well as proteolytic enzymes (MASP-1, MASP-2, MASP-3), the group includes non-enzymatic factors (MAp19, MAp44) . In this review, the association-specific factors of the lectin pathway with haematologic malignancies and related infections are discussed.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 31.6 kDa. The protein migrates as 38-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

P48740-2

Expression Region

Ile 450 - Val 721

Host

HEK293

Target

MASP3

Conjugation

Unconjugated

Tag

C-10xHis

Source

Human

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

95%

Format

Powder

Buffer

50 mM Tris, 150 mM NaCl, pH7.5

Additives

Trehalose

Molecular Weight

31.6 kDa

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/MA3-H52H3.pdf

Species

Human

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