SGC-CLK-1
SGC-CLK-1, a chemical probe, is a potent and selective inhibitor of Cdc2-like kinases CLK1, CLK2, and CLK4. SGC-CLK-1 can inhibit the growth of melanoma and glioblastoma cells[1].
Product Specifications
CAS Number
[748142-15-6]
Product Name Alternative
CAF-170
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sgc-clk-1.html
Concentration
10mM
Purity
99.12
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
FC(F)(C1=CC(NC2=NC=CC(C3=C4C=CC(OC)=NN4N=C3)=N2)=CC(OC)=C1)F
Molecular Formula
C19H15F3N6O2
Molecular Weight
416.36
References & Citations
[1]Tiek D, et, al. SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4. Curr Res Chem Biol. 2023:3:100045.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
VAng-Cr7341-500gEcoli 500 µg (E. coli)
Recombinant Pasteurella Multocida rpsH Protein (aa 1-130)
Sign In for Pricing
View Details M1500-01-PE 100 µL
MADD (MAP Kinase-activating Death Domain Protein, Differentially Expressed in Normal and Neoplastic Cells, DENN, Insulinoma Glucagonoma Clone 20, IG20, KIAA0358, Rab3 GDP/GTP Exchange Factor, RAB3GEP) (PE) discontinued
Sign In for Pricing
View Details YP-W72686-01 48 Tests
Rabbit Bone morphogenetic protein (BMP) ELISA Kit
Sign In for Pricing
View Details 
YP-W72686-02 96 Tests
Rabbit Bone morphogenetic protein (BMP) ELISA Kit
Sign In for Pricing
View Details 