SGC-CLK-1
SGC-CLK-1, a chemical probe, is a potent and selective inhibitor of Cdc2-like kinases CLK1, CLK2, and CLK4. SGC-CLK-1 can inhibit the growth of melanoma and glioblastoma cells[1].
Product Specifications
CAS Number
[748142-15-6]
Product Name Alternative
CAF-170
UNSPSC
12352005
Target
CDK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sgc-clk-1.html
Concentration
10mM
Purity
99.12
Solubility
DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
FC(F)(C1=CC(NC2=NC=CC(C3=C4C=CC(OC)=NN4N=C3)=N2)=CC(OC)=C1)F
Molecular Formula
C19H15F3N6O2
Molecular Weight
416.36
References & Citations
[1]Tiek D, et, al. SGC-CLK-1: A chemical probe for the Cdc2-like kinases CLK1, CLK2, and CLK4. Curr Res Chem Biol. 2023:3:100045.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
K7535005 3x 1.0 µg
Gnas sgRNA CRISPR/Cas9 All-in-One Lentivector set (Rat)
Sign In for Pricing
View Details 
FAB7977S-100UG 100 µg
Human GPR64 Alexa Fluor 750 MAb (Clone 206420)
Sign In for Pricing
View Details 
ELK6263MS-01 48 Tests
Rat cTnT/TNNT2 (Troponin T Type 2, Cardiac) Microsample ELISA Kit
Sign In for Pricing
View Details ELK6263MS-02 96 Tests
Rat cTnT/TNNT2 (Troponin T Type 2, Cardiac) Microsample ELISA Kit
Sign In for Pricing
View Details