DIO2 Antibody (Center) [APR07583G]
Product Specifications
Background
Tissue Location: Isoform 1 is expressed in the lung, trachea, kidney, heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain (PubMed:8755651, PubMed:11165050) . Isoform 2 is expressed in the brain, heart, kidney and trachea (PubMed:11165050)
Synonyms
Type II iodothyronine deiodinase, 5DII, DIOII, Type 2 DI, Type-II 5'-deiodinase, DIO2, ITDI2, TXDI2
Gene Name
DIO2
Gene ID
1734
UniProt
Q92813
Chromosomal Location
Membrane; Single-pass membrane protein
Applications
WB, IHC-P, FC
Dilution
WB--1:500-2000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Responsible for the deiodination of T4 (3,5,3',5'- tetraiodothyronine) into T3 (3,5,3'-triiodothyronine) . Essential for providing the brain with appropriate levels of T3 during the critical period of development.
Molecular Weight
30552
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DIO2 Antibody (Center) [APR07583G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1734
Uniprot URL
https://www.uniprot.org/uniprot/Q92813
Available Sizes
Curated Selection
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