HK2 (Hexokinase II) Antibody (Center) [APR07762G]
Product Specifications
Background
Tissue Location: Predominant hexokinase isozyme expressed in insulin-responsive tissues such as skeletal muscle
Synonyms
Hexokinase-2, Hexokinase type II, HK II, Muscle form hexokinase, HK2
Gene Name
HGNC:4923
Gene ID
3099
UniProt
P52789
Chromosomal Location
Mitochondrion outer membrane; Peripheral membrane protein. Cytoplasm, cytosol Note=The mitochondrial-binding peptide (MBP) region promotes association with the mitochondrial outer membrane (PubMed:29298880) The interaction with the mitochondrial outer membrane via the mitochondrial-binding peptide (MBP) region promotes higher stability of the protein (PubMed:29298880) . Release from the mitochondrial outer membrane into the cytosol induces permeability transition pore (PTP) opening and apoptosis (PubMed:18350175) .
Applications
WB, IHC-P
Dilution
IHC-P--1:100 WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Function
2318501726985301292988802929888018350175
Molecular Weight
102380
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HK2 (Hexokinase II) Antibody (Center) [APR07762G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3099
Uniprot URL
https://www.uniprot.org/uniprot/P52789
Available Sizes
Curated Selection
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