SPAK Antibody (Center) [APR06998G]
Product Specifications
Background
Tissue Location: Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis
Synonyms
STE20/SPS1-related proline-alanine-rich protein kinase, Ste-20-related kinase, DCHT, Serine/threonine-protein kinase 39, STK39, SPAK
Gene Name
STK39
Gene ID
27347
UniProt
Q9UEW8
Chromosomal Location
Cytoplasm. Nucleus. Note=Nucleus when caspase-cleaved.
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
May act as a mediator of stress-activated signals. Mediates the inhibition of SLC4A4, SLC26A6 as well as CFTR activities by the WNK scaffolds, probably through phosphorylation. Phosphorylates RELT.
Molecular Weight
59474
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPAK Antibody (Center) [APR06998G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=27347
Uniprot URL
https://www.uniprot.org/uniprot/Q9UEW8
Available Sizes
Curated Selection
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