What is the catalog number for IPF Antibody (C-term) [APR08022G]?

The catalog number for IPF Antibody (C-term) [APR08022G] is APR08022G.

What sizes are available for IPF Antibody (C-term) [APR08022G]?

IPF Antibody (C-term) [APR08022G] is available in the following size(s): 50 µL, 100 µL, 200 µL, 400 µL.

How many pack sizes does IPF Antibody (C-term) [APR08022G] come in?

IPF Antibody (C-term) [APR08022G] is available in 4 different pack sizes.

Is IPF Antibody (C-term) [APR08022G] in stock?

IPF Antibody (C-term) [APR08022G] is currently made to order / not held in immediate stock. Contact us for lead time.

IPF Antibody (C-term) [APR08022G]

Product Specifications

Background

Tissue Location: Duodenum and pancreas (Langerhans islet beta cells and small subsets of endocrine non-beta-cells, at low levels in acinar cells)

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IPF Antibody (C-term) [APR08022G].

Synonyms

Pancreas/duodenum homeobox protein 1, PDX-1, Glucose-sensitive factor, GSF, Insulin promoter factor 1, IPF-1, Insulin upstream factor 1, IUF-1, Islet/duodenum homeobox-1, IDX-1, Somatostatin-transactivating factor 1, STF-1, PDX1, IPF1, STF1

Gene Name

PDX1

Gene ID

3651

UniProt

P52945

Chromosomal Location

Nucleus. Cytoplasm, cytosol.

Applications

IF, WB

Dilution

WB--1:1000 IF--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

Activates insulin, somatostatin, glucokinase, islet amyloid polypeptide and glucose transporter type 2 gene transcription. Particularly involved in glucose-dependent regulation of insulin gene transcription. As part of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells is involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element. Binds preferentially the DNA motif 5'-[CT]TAAT[TG]-3'. During development, specifies the early pancreatic epithelium, permitting its proliferation, branching and subsequent differentiation. At adult stage, required for maintaining the hormone-producing phenotype of the beta-cell.