SPHK1 Antibody (Center) [APR06976G]
Product Specifications
Background
Tissue Location: Widely expressed with highest levels in adult liver, kidney, heart and skeletal muscle. Expressed in brain cortex (at protein level) (PubMed:29662056) .
Synonyms
Sphingosine kinase 1, SK 1, SPK 1, SPHK1, SPHK, SPK
Gene Name
HGNC:11240
Gene ID
8877
UniProt
Q9NYA1
Chromosomal Location
Cytoplasm. Nucleus. Cell membrane. Endosome membrane; Peripheral membrane protein. Membrane, clathrin-coated pit. Cell junction, synapse {ECO:0000250|UniProtKB:Q8CI15}. Note=Translocated from the cytoplasm to the plasma membrane in a CIB1-dependent manner (PubMed:19854831) . Binds to membranes containing negatively charged lipids but not neutral lipids (PubMed:24929359) . Recruited to endocytic membranes by sphingosine where promotes membrane fusion (By similarity) {ECO:0000250|UniProtKB:Q8CI15, ECO:0000269|PubMed:19854831, ECO:0000269|PubMed:24929359}
Applications
WB, IHC-P
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
2057721423602659296620562492935911923095161182192057721423935096280497342492935925417698
Molecular Weight
42518
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SPHK1 Antibody (Center) [APR06976G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=8877
Uniprot URL
https://www.uniprot.org/uniprot/Q9NYA1
Available Sizes
Curated Selection
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