FOLR2 Antibody (N-term) [AMM04583G]
Product Specifications
Background
Tissue Location: Expressed in placenta and hematopoietic cells. Expression is increased in malignant tissues
Synonyms
Folate receptor beta, FR-beta, Folate receptor 2, Folate receptor, fetal/placental, Placental folate-binding protein, FBP, FOLR2
Gene Name
FOLR2
Gene ID
2350
UniProt
P14207
Chromosomal Location
Cell membrane; Lipid-anchor, GPI-anchor. Secreted
Applications
WB, IHC-P, FC
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH. Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release.
Molecular Weight
29280
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FOLR2 Antibody (N-term) [AMM04583G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2350
Uniprot URL
https://www.uniprot.org/uniprot/P14207
Available Sizes
Curated Selection
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