ITPA Antibody (N-term) [APR08049G]
Product Specifications
Background
Tissue Location: Ubiquitous. Highly expressed in heart, liver, sex glands, thyroid and adrenal gland
Synonyms
Inosine triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, ITPase {ECO:0000255|HAMAP-Rule:MF_03148}, Inosine triphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, 36119 {ECO:0000255|HAMAP-Rule:MF_03148}, Non-canonical purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, Non-standard purine NTP pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, Nucleoside-triphosphate diphosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, Nucleoside-triphosphate pyrophosphatase {ECO:0000255|HAMAP-Rule:MF_03148}, NTPase {ECO:0000255|HAMAP-Rule:MF_03148}, Putative oncogene protein hlc14-06-p, ITPA {ECO:0000255|HAMAP-Rule:MF_03148}, C20orf37
Gene Name
ITPA {ECO:0000255|HAMAP-Rule:MF_03148}
Gene ID
3704
UniProt
Q9BY32
Chromosomal Location
Cytoplasm {ECO:0000255|HAMAP-Rule:MF_03148, ECO:0000269|PubMed:11278832}
Applications
IHC-P, FC, IF, WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Pyrophosphatase that hydrolyzes the non-canonical purine nucleotides inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) as well as 2'-deoxy-N-6-hydroxylaminopurine triposphate (dHAPTP) and xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions.
Molecular Weight
21446
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ITPA Antibody (N-term) [APR08049G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3704
Uniprot URL
https://www.uniprot.org/uniprot/Q9BY32
Available Sizes
Curated Selection
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