DOCK2 Antibody (C-term) [APR15796G]
Product Specifications
Background
Tissue Location: Specifically expressed in hematopoietic cells. Highly expressed in peripheral blood leukocytes, and expressed at intermediate level in thymus and spleen. Expressed at very low level in the small intestine and colon.
Synonyms
Dedicator of cytokinesis protein 2, DOCK2, KIAA0209
Gene Name
DOCK2
Gene ID
1794
UniProt
Q92608
Chromosomal Location
Endomembrane system; Peripheral membrane protein. Cytoplasm, cytoskeleton. Note=Colocalizes with F-actin
Applications
WB
Dilution
WB--1:2000
Function
Involved in cytoskeletal rearrangements required for lymphocyte migration in response of chemokines. Activates RAC1 and RAC2, but not CDC42, by functioning as a guanine nucleotide exchange factor (GEF), which exchanges bound GDP for free GTP. May also participate in IL2 transcriptional activation via the activation of RAC2.
Molecular Weight
211948
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DOCK2 Antibody (C-term) [APR15796G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1794
Uniprot URL
https://www.uniprot.org/uniprot/Q92608
Available Sizes
Curated Selection
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