Mouse Sirt1 Antibody (C-term) [APR08500G]

Product Specifications

Background

Tissue Location: Widely expressed. Weakly expressed in liver and skeletal muscle.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Mouse Sirt1 Antibody (C-term) [APR08500G].

Synonyms

NAD-dependent protein deacetylase sirtuin-1, 351-, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, SIR2alpha, Sir2, mSIR2a, SirtT1 75 kDa fragment, 75SirT1, Sirt1, Sir2l1

Gene Name

Sirt1

Gene ID

93759

UniProt

Q923E4

Chromosomal Location

Nucleus, PML body {ECO:0000250|UniProtKB:Q96EB6}. Cytoplasm Nucleus. Note=Colocalizes in the nucleus with XBP1 isoform 2. Recruited to the nuclear bodies via its interaction with PML. Colocalized with APEX1 in the nucleus. May be found in nucleolus, nuclear euchromatin, heterochromatin and inner membrane (By similarity) . Shuttles between nucleus and cytoplasm (PubMed:17197703) {ECO:0000250|UniProtKB:Q96EB6, ECO:0000269|PubMed:17197703}

Applications

WB, IF, IHC-P

Dilution

WB--1:2000 IHC-P--1:100~500 IF--1:25 WB--1:1000

Function

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Molecular Weight

80372

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.