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R Cask Antibody (Center) [APR13040G]

Product Specifications

Background

Tissue Location: Expressed in the foot process layer of podocytes in the kidney glomerulus and in tubules (at protein level) . Detected in brain and neurons.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality R Cask Antibody (Center) [APR13040G].

Synonyms

Peripheral plasma membrane protein CASK, Calcium/calmodulin-dependent serine protein kinase, Cask

Gene Name

Cask

Gene ID

29647

UniProt

Q62915

Chromosomal Location

Nucleus. Cytoplasm. Cell membrane; Peripheral membrane protein

Applications

WB

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Multidomain scaffolding protein with a role in synaptic transmembrane protein anchoring and ion channel trafficking. Contributes to neural development and regulation of gene expression via interaction with the transcription factor TBR1. Binds to cell-surface proteins, including amyloid precursor protein, neurexins, and syndecans. May mediate a link between the extracellular matrix and the actin cytoskeleton via its interaction with syndecan and with the actin/spectrin-binding protein 4.1. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules (By similarity) .

Molecular Weight

103259

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=29647

Uniprot URL

https://www.uniprot.org/uniprot/Q62915

Available Sizes

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