SFN Antibody (Center) [APR13281G]
Product Specifications
Background
Tissue Location: Present mainly in tissues enriched in stratified squamous keratinizing epithelium
Synonyms
14-3-3 protein sigma, Epithelial cell marker protein 1, Stratifin, SFN, HME1
Gene Name
SFN
Gene ID
2810
UniProt
P31947
Chromosomal Location
Cytoplasm. Nucleus. Secreted. Note=May be secreted by a non-classical secretory pathway
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. When bound to KRT17, regulates protein synthesis and epithelial cell growth by stimulating Akt/mTOR pathway. May also regulate MDM2 autoubiquitination and degradation and thereby activate p53/TP53.
Molecular Weight
27774
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SFN Antibody (Center) [APR13281G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=2810
Uniprot URL
https://www.uniprot.org/uniprot/P31947
Available Sizes
Curated Selection
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