DHCR7 Antibody (C-term) [APR07556G]

Product Specifications

Background

Tissue Location: Widely expressed. Most abundant in adrenal gland, liver, testis, and brain.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DHCR7 Antibody (C-term) [APR07556G].

Synonyms

7-dehydrocholesterol reductase, 7-DHC reductase, Putative sterol reductase SR-2, Sterol Delta (7) -reductase, DHCR7, D7SR

Gene Name

DHCR7

Gene ID

1717

UniProt

Q9UBM7

Chromosomal Location

Endoplasmic reticulum membrane; Multi-pass membrane protein

Applications

WB, IHC-P, IF

Dilution

WB--1:2000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

7-dehydrocholesterol reductase of the cholesterol biosynthetic pathway reducing the C7-C8 double bond of cholesta-5,7- dien-3beta-ol (7-dehydrocholesterol/7-DHC) and cholesta-5,7,24-trien- 3beta-ol, two intermediates in that pathway.