TLR4 Antibody (Center) [AMM05418G]
Product Specifications
Background
Tissue Location: Highly expressed in placenta, spleen and peripheral blood leukocytes (PubMed:9435236, PubMed:9237759) . Detected in monocytes, macrophages, dendritic cells and several types of T-cells (PubMed:9237759, PubMed:27022195) .
Synonyms
Toll-like receptor 4, hToll, CD284, TLR4
Gene Name
TLR4
Gene ID
7099
UniProt
O00206
Chromosomal Location
Cell membrane; Single-pass type I membrane protein. Early endosome. Cell projection, ruffle {ECO:0000250|UniProtKB:Q9QUK6}. Note=Upon complex formation with CD36 and TLR6, internalized through dynamin-dependent endocytosis (PubMed:20037584) . Colocalizes with RFTN1 at cell membrane and then together with RFTN1 moves to endosomes, upon lipopolysaccharide stimulation.
Applications
WB, FC
Dilution
WB--1:1000 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
2702219592377591083563427022195213931022071119215809303238801871662220510835634158093031747872920037584207111922388018727022195923775929038465
Molecular Weight
95680
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TLR4 Antibody (Center) [AMM05418G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=7099
Uniprot URL
https://www.uniprot.org/uniprot/O00206
Available Sizes
Curated Selection
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