KCNJ11 Antibody (N-term) [APR08077G]
Product Specifications
Synonyms
ATP-sensitive inward rectifier potassium channel 11, IKATP, Inward rectifier K (+) channel Kir62, Potassium channel, inwardly rectifying subfamily J member 11, KCNJ11
Gene Name
KCNJ11
Gene ID
3767
UniProt
Q14654
Chromosomal Location
Membrane; Multi-pass membrane protein.
Applications
WB, FC
Dilution
WB--1:1000 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium (By similarity) . Subunit of ATP-sensitive potassium channels (KATP) . Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.
Molecular Weight
43541
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNJ11 Antibody (N-term) [APR08077G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=3767
Uniprot URL
https://www.uniprot.org/uniprot/Q14654
Available Sizes
Curated Selection
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