RPGRIP1 Antibody (Center) [APR13147G]
Product Specifications
Background
Tissue Location: Strong expression in retina, with weaker expression in testis. Expressed in other neurons such as amacrine cells Colocalizes with RGPR in the outer segment of rod photoreceptors and cone outer segments.
Synonyms
X-linked retinitis pigmentosa GTPase regulator-interacting protein 1, RPGR-interacting protein 1, RPGRIP1
Gene Name
RPGRIP1
Gene ID
57096
UniProt
Q96KN7
Chromosomal Location
Cell projection, cilium. Note=Situated between the axonemal microtubules and the plasma membrane (By similarity) . In the retinal photoreceptor cell layer, localizes at the connecting cilium, a thin bridge linking the cell body and the light-sensing outer segment (By similarity) . Colocalizes with RGPR in the photoreceptor connecting cilium (By similarity) . {ECO:0000250|UniProtKB:Q9EPQ2}
Applications
WB, IHC-P, FC
Dilution
WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
May function as scaffolding protein. Required for normal location of RPGR at the connecting cilium of photoreceptor cells. Required for normal disk morphogenesis and disk organization in the outer segment of photoreceptor cells and for survival of photoreceptor cells.
Molecular Weight
146682
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RPGRIP1 Antibody (Center) [APR13147G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=57096
Uniprot URL
https://www.uniprot.org/uniprot/Q96KN7
Available Sizes
Curated Selection
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