JAKMIP1 Antibody (Center) [APR12445G]

Product Specifications

Background

Tissue Location: Predominantly expressed in neural tissues and lymphoid cells (at protein level) . Isoform 2, isoform 3 and isoform 4 are specifically expressed in brain and retina. Isoform 1 and isoform 5 are also detected in liver, lung and skeletal muscle. Also detected in testis and to a lower extent spleen and intestine

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality JAKMIP1 Antibody (Center) [APR12445G].

Synonyms

Janus kinase and microtubule-interacting protein 1, GABA-B receptor-binding protein, Multiple alpha-helices and RNA-linker protein 1, Marlin-1, JAKMIP1, GABABRBP, JAMIP1, MARLIN1

Gene Name

JAKMIP1

Gene ID

152789

UniProt

Q96N16

Chromosomal Location

Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein. Note=Colocalizes with the microtubule network Localizes to the cell body and neurites of hippocampal neurons where it accumulates in granules. Localizes to the tail and to a lower extent to the head of sperm cells

Applications

WB, IHC-P

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Associates with microtubules and may play a role in the microtubule-dependent transport of the GABA-B receptor. May play a role in JAK1 signaling and regulate microtubule cytoskeleton rearrangements.