CTDSP1-V250 Antibody (C-term) [APR15619G]
Product Specifications
Background
Tissue Location: Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta
Synonyms
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, Nuclear LIM interactor-interacting factor 3, NLI-IF, NLI-interacting factor 3, Small C-terminal domain phosphatase 1, SCP1, Small CTD phosphatase 1, CTDSP1, NIF3, NLIIF, SCP1
Gene Name
CTDSP1
Gene ID
58190
UniProt
Q9GZU7
Chromosomal Location
Nucleus. Note=Colocalizes with RNA polymerase II
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Molecular Weight
29203
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CTDSP1-V250 Antibody (C-term) [APR15619G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=58190
Uniprot URL
https://www.uniprot.org/uniprot/Q9GZU7
Available Sizes
Curated Selection
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