PACSIN3 Antibody (N-term) [APR17734G]
Product Specifications
Background
Tissue Location: Widely expressed, with highest levels in heart and skeletal muscle, intermediate levels in placenta, liver and pancreas, and very low levels in brain, lung and kidney
Synonyms
Protein kinase C and casein kinase substrate in neurons protein 3, SH3 domain-containing protein 6511, PACSIN3
Gene Name
PACSIN3
Gene ID
29763
UniProt
Q9UKS6
Chromosomal Location
Cytoplasm. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Detected at the inner aspect of the plasma membrane in myotubes.
Applications
IHC-P, WB
Dilution
WB--1:2000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Function
Plays a role in endocytosis and regulates internalization of plasma membrane proteins. Overexpression impairs internalization of SLC2A1/GLUT1 and TRPV4 and increases the levels of SLC2A1/GLUT1 and TRPV4 at the cell membrane. Inhibits the TRPV4 calcium channel activity (By similarity) .
Molecular Weight
48487
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PACSIN3 Antibody (N-term) [APR17734G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=29763
Uniprot URL
https://www.uniprot.org/uniprot/Q9UKS6
Available Sizes
Curated Selection
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