PRKX Antibody (C-term) [APR14381G]
Product Specifications
Background
Tissue Location: Widely expressed (at protein level) . Specifically expressed in blood by macrophages and granulocytes according to PubMed:9860982.
Synonyms
CAMP-dependent protein kinase catalytic subunit PRKX, PrKX, Protein kinase X, Protein kinase X-linked, Serine/threonine-protein kinase PRKX, Protein kinase PKX1, PRKX, PKX1
Gene Name
PRKX
Gene ID
5613
UniProt
P51817
Chromosomal Location
Cytoplasm. Nucleus. Note=cAMP induces nuclear translocation
Applications
IHC-P
Dilution
IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular- like structure formation.
Molecular Weight
40896
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PRKX Antibody (C-term) [APR14381G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5613
Uniprot URL
https://www.uniprot.org/uniprot/P51817
Available Sizes
Curated Selection
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