MUC20 Antibody (C-term) [APR14363G]
Product Specifications
Background
Tissue Location: Highly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules Detected in most of the male urogenital tract epithelia, with the exception of epididymis.
Synonyms
Mucin-20, MUC-20, MUC20, KIAA1359
Gene Name
MUC20
Gene ID
200958
UniProt
Q8N307
Chromosomal Location
Secreted. Apical cell membrane. Basolateral cell membrane. Cell projection, microvillus membrane
Applications
WB, IHC-P-Leica, IF, FC
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF) -induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.
Molecular Weight
71982
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MUC20 Antibody (C-term) [APR14363G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=200958
Uniprot URL
https://www.uniprot.org/uniprot/Q8N307
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
