DOK4 Antibody (C-term) [APR11268G]
Product Specifications
Background
Tissue Location: Widely expressed. High expression in skeletal muscle, heart, kidney and liver. Weaker expression in spleen, lung and small intestine, brain, heart and. Expressed in both resting and activated peripheral blood T-cells.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DOK4 Antibody (C-term) [APR11268G].
Synonyms
Docking protein 4, Downstream of tyrosine kinase 4, Insulin receptor substrate 5, IRS-5, IRS5, DOK4
Gene Name
DOK4
Gene ID
55715
UniProt
Q8TEW6
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK4 functions in RET-mediated neurite outgrowth and plays a positive role in activation of the MAP kinase pathway (By similarity) . Putative link with downstream effectors of RET in neuronal differentiation. May be involved in the regulation of the immune response induced by T-cells.
Molecular Weight
37028
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=55715
Uniprot URL
https://www.uniprot.org/uniprot/Q8TEW6
Available Sizes
Frequently Asked Questions
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