LTK Antibody (N-term) [APR08288G]
Product Specifications
Background
Tissue Location: Expressed in non-hematopoietic cell lines and T- and B-cell lines.
Synonyms
Leukocyte tyrosine kinase receptor, Protein tyrosine kinase 1, LTK, TYK1
Gene Name
LTK
Gene ID
4058
UniProt
P29376
Chromosomal Location
Membrane; Single-pass type I membrane protein.
Applications
WB
Dilution
WB--1:2000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
Receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport.
Molecular Weight
91681
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality LTK Antibody (N-term) [APR08288G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=4058
Uniprot URL
https://www.uniprot.org/uniprot/P29376
Available Sizes
Curated Selection
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