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CLK1 Antibody (N-term) [APR15518G]

Product Specifications

Background

Tissue Location: Endothelial cells..

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CLK1 Antibody (N-term) [APR15518G].

Synonyms

Dual specificity protein kinase CLK1, CDC-like kinase 1, CLK1, CLK

Gene Name

CLK1

Gene ID

1195

UniProt

P49759

Chromosomal Location

Nucleus.

Applications

WB

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Function

Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA.

Molecular Weight

57291

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=1195

Uniprot URL

https://www.uniprot.org/uniprot/P49759

Available Sizes

Frequently Asked Questions

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