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FASN Antibody (Center) [AMM04512G]

Product Specifications

Background

Tissue Location: Ubiquitous. Prominent expression in brain, lung, liver and mammary gland.

Synonyms

Fatty acid synthase, [Acyl-carrier-protein] S-acetyltransferase, [Acyl-carrier-protein] S-malonyltransferase, 3-oxoacyl-[acyl-carrier-protein] synthase, 3-oxoacyl-[acyl-carrier-protein] reductase, 3-hydroxyacyl-[acyl-carrier-protein] dehydratase, Enoyl-[acyl-carrier-protein] reductase, Oleoyl-[acyl-carrier-protein] hydrolase, FASN, FAS

Gene Name

FASN

Gene ID

2194

UniProt

P49327

Chromosomal Location

Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV

Applications

IF, WB, IHC-P, FC

Dilution

WB--1:16000 IF--1:200 WB--1:1000 IF--1:10~50 IHC-P--1:100~500 FC--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

Fatty acid synthetase is a multifunctional enzyme that catalyzes the de novo biosynthesis of long-chain saturated fatty acids starting from acetyl-CoA and malonyl-CoA in the presence of NADPH. This multifunctional protein contains 7 catalytic activities and a site for the binding of the prosthetic group 4'-phosphopantetheine of the acyl carrier protein ([ACP]) domain.

Molecular Weight

273427

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality FASN Antibody (Center) [AMM04512G].

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=2194

Uniprot URL

https://www.uniprot.org/uniprot/P49327

Available Sizes

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