PKA C-alpha/PKA C-beta Antibody (N-term) [AMR09295G]

Product Specifications

Background

Tissue Location: Isoform 1 is ubiquitous. Isoform 2 is sperm- specific and is enriched in pachytene spermatocytes but is not detected in round spermatids.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PKA C-alpha/PKA C-beta Antibody (N-term) [AMR09295G].

Synonyms

CAMP-dependent protein kinase catalytic subunit alpha, PKA C-alpha, PRKACA, PKACA

Gene Name

PRKACA

Gene ID

5566

UniProt

P17612

Chromosomal Location

Cytoplasm. Cell membrane. Nucleus. Mitochondrion. Membrane; Lipid-anchor. Note=Translocates into the nucleus (monomeric catalytic subunit) . The inactive holoenzyme is found in the cytoplasm Distributed throughout the cytoplasm in meiotically incompetent oocytes. Associated to mitochondrion as meiotic competence is acquired Aggregates around the germinal vesicles (GV) at the immature GV stage oocytes (By similarity) . Colocalizes with HSF1 in nuclear stress bodies (nSBs) upon heat shock (PubMed:21085490) . {ECO:0000250, ECO:0000269|PubMed:21085490}

Applications

WB, IHC-P

Dilution

WB--1:1000

Form

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

Function

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