PKA C-alpha/PKA C-beta Antibody (N-term) [AMR09295G]

Tissue Location: Isoform 1 is ubiquitous. Isoform 2 is sperm- specific and is enriched in pachytene spermatocytes but is not detected in round spermatids.

Cytoplasm. Cell membrane. Nucleus. Mitochondrion. Membrane; Lipid-anchor. Note=Translocates into the nucleus (monomeric catalytic subunit) . The inactive holoenzyme is found in the cytoplasm Distributed throughout the cytoplasm in meiotically incompetent oocytes. Associated to mitochondrion as meiotic competence is acquired Aggregates around the germinal vesicles (GV) at the immature GV stage oocytes (By similarity) . Colocalizes with HSF1 in nuclear stress bodies (nSBs) upon heat shock (PubMed:21085490) . {ECO:0000250, ECO:0000269|PubMed:21085490}

Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.

15642694159051761638784717333334175659871769341218836454199498372035684121085490215142752181298415642694159051761638784717333334175659871769341218836454199498372035684121085490215142752181298421423175215142751994983715642694203568411733333417693412175659871590517615642694163878471883645421085490

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PKA C-alpha/PKA C-beta Antibody (N-term) [AMR09295G].