PKA C-alpha/PKA C-beta Antibody (N-term) [AMR09295G]
Product Specifications
Background
Tissue Location: Isoform 1 is ubiquitous. Isoform 2 is sperm- specific and is enriched in pachytene spermatocytes but is not detected in round spermatids.
Synonyms
CAMP-dependent protein kinase catalytic subunit alpha, PKA C-alpha, PRKACA, PKACA
Gene Name
PRKACA
Gene ID
5566
UniProt
P17612
Chromosomal Location
Cytoplasm. Cell membrane. Nucleus. Mitochondrion. Membrane; Lipid-anchor. Note=Translocates into the nucleus (monomeric catalytic subunit) . The inactive holoenzyme is found in the cytoplasm Distributed throughout the cytoplasm in meiotically incompetent oocytes. Associated to mitochondrion as meiotic competence is acquired Aggregates around the germinal vesicles (GV) at the immature GV stage oocytes (By similarity) . Colocalizes with HSF1 in nuclear stress bodies (nSBs) upon heat shock (PubMed:21085490) . {ECO:0000250, ECO:0000269|PubMed:21085490}
Applications
WB, IHC-P
Dilution
WB--1:1000
Form
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
Function
15642694159051761638784717333334175659871769341218836454199498372035684121085490215142752181298415642694159051761638784717333334175659871769341218836454199498372035684121085490215142752181298421423175215142751994983715642694203568411733333417693412175659871590517615642694163878471883645421085490
Molecular Weight
40590
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PKA C-alpha/PKA C-beta Antibody (N-term) [AMR09295G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5566
Uniprot URL
https://www.uniprot.org/uniprot/P17612
Available Sizes
Curated Selection
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