PAX6-T373 Antibody [APR12742G]
Product Specifications
Background
Tissue Location: [Isoform 1]: Expressed in lymphoblasts.
Synonyms
Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6, AN2
Gene Name
PAX6
Gene ID
5080
UniProt
P26367
Chromosomal Location
Nucleus {ECO:0000250|UniProtKB:P63015}. [Isoform 5a]: Nucleus {ECO:0000250|UniProtKB:P63016}
Applications
WB, IHC-P, IF
Dilution
WB--1:2000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity) . Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity) . Acts as a transcriptional repressor of NFATC1- mediated gene expression (By similarity) .
Molecular Weight
46683
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PAX6-T373 Antibody [APR12742G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5080
Uniprot URL
https://www.uniprot.org/uniprot/P26367
Available Sizes
Curated Selection
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