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KCNJ2 Antibody (C-term) [AMM06108G]

Product Specifications

Background

Tissue Location: Heart, brain, placenta, lung, skeletal muscle, and kidney. Diffusely distributed throughout the brain

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality KCNJ2 Antibody (C-term) [AMM06108G].

Synonyms

Inward rectifier potassium channel 2, Cardiac inward rectifier potassium channel, Inward rectifier K (+) channel Kir21, IRK-1, hIRK1, Potassium channel, inwardly rectifying subfamily J member 2, KCNJ2, IRK1

Gene Name

KCNJ2

Gene ID

3759

UniProt

P63252

Chromosomal Location

Membrane; Multi-pass membrane protein. Membrane; Lipid-anchor

Applications

WB, IHC-P, FC

Dilution

WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium.

Molecular Weight

48288

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=3759

Uniprot URL

https://www.uniprot.org/uniprot/P63252

Available Sizes

Frequently Asked Questions

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