CRHR2 Antibody (Center) [AMM05792G]
Product Specifications
Synonyms
Corticotropin-releasing factor receptor 2, CRF-R-2, CRF-R2, CRFR-2, Corticotropin-releasing hormone receptor 2, CRH-R-2, CRH-R2, CRHR2, CRF2R, CRH2R
Gene Name
CRHR2
Gene ID
1395
UniProt
Q13324
Chromosomal Location
Cell membrane; Multi-pass membrane protein
Applications
FC, WB, IHC-P, IF
Dilution
FC--1:10~50 WB--1:1000 IHC-P--1:100~500 IF--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
G-protein coupled receptor for CRH (corticotropin-releasing factor), UCN (urocortin), UCN2 and UCN3. Has high affinity for UCN. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and down-stream effectors, such as adenylate cyclase. Promotes the activation of adenylate cyclase, leading to increased intracellular cAMP levels.
Molecular Weight
47688
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CRHR2 Antibody (Center) [AMM05792G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=1395
Uniprot URL
https://www.uniprot.org/uniprot/Q13324
Available Sizes
Curated Selection
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