NKRF Antibody (Center) [APR17581G]
Product Specifications
Background
Tissue Location: Widely and constitutively expressed. Expressed at lower level in colon, peripheral blood lymphocytes, lung and kidney
Synonyms
NF-kappa-B-repressing factor, NFkB-repressing factor, Protein ITBA4, Transcription factor NRF, NKRF, ITBA4, NRF
Gene Name
NKRF
Gene ID
55922
UniProt
O15226
Chromosomal Location
Nucleus, nucleolus.
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
Interacts with a specific negative regulatory element (NRE) 5'-AATTCCTCTGA-3' to mediate transcriptional repression of certain NK- kappa-B responsive genes. Involved in the constitutive silencing of the interferon beta promoter, independently of the virus-induced signals, and in the inhibition of the basal and cytokine-induced iNOS promoter activity. Also involved in the regulation of IL-8 transcription.
Molecular Weight
77673
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality NKRF Antibody (Center) [APR17581G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=55922
Uniprot URL
https://www.uniprot.org/uniprot/O15226
Available Sizes
Curated Selection
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