What is the catalog number for EMD Antibody (C-term) [APR15819G]?

The catalog number for EMD Antibody (C-term) [APR15819G] is APR15819G.

What sizes are available for EMD Antibody (C-term) [APR15819G]?

EMD Antibody (C-term) [APR15819G] is available in the following size(s): 50 µL, 100 µL, 200 µL, 400 µL.

How many pack sizes does EMD Antibody (C-term) [APR15819G] come in?

EMD Antibody (C-term) [APR15819G] is available in 4 different pack sizes.

Is EMD Antibody (C-term) [APR15819G] in stock?

EMD Antibody (C-term) [APR15819G] is currently made to order / not held in immediate stock. Contact us for lead time.

EMD Antibody (C-term) [APR15819G]

Product Specifications

Background

Tissue Location: Skeletal muscle, heart, colon, testis, ovary and pancreas

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality EMD Antibody (C-term) [APR15819G].

Synonyms

Emerin, EMD, EDMD, STA

Gene Name

EMD

Gene ID

2010

UniProt

P50402

Chromosomal Location

Nucleus inner membrane; Single-pass membrane protein; Nucleoplasmic side. Nucleus outer membrane. Note=Colocalized with BANF1 at the central region of the assembling nuclear rim, near spindle-attachment sites. The accumulation of different intermediates of prelamin-A/C (non-farnesylated or carboxymethylated farnesylated prelamin-A/C) in fibroblasts modify its localization in the nucleus

Applications

WB, FC

Dilution

WB--1:1000 FC--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta- catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1- dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.