ABCB4 Antibody (Center) [APR07047G]
Product Specifications
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ABCB4 Antibody (Center) [APR07047G].
Synonyms
Multidrug resistance protein 3, ATP-binding cassette sub-family B member 4, P-glycoprotein 3, ABCB4, MDR3, PGY3
Gene Name
HGNC:45
Gene ID
5244
UniProt
P21439
Chromosomal Location
Cell membrane; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}. Apical cell membrane; Multi-pass membrane protein {ECO:0000255|PROSITE-ProRule:PRU00441}. Membrane raft. Cytoplasm Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000250|UniProtKB:Q08201}. Note=Localized at the apical canalicular membrane of the epithelial cells lining the lumen of the bile canaliculi and biliary ductules (By similarity) . Transported from the Golgi to the apical bile canalicular membrane in a RACK1-dependent manner (PubMed:19674157) . Redistributed into pseudocanaliculi formed between cells in a bezafibrate- or PPARA-dependent manner (PubMed:15258199) . Localized preferentially in lipid nonraft domains of canalicular plasma membranes (PubMed:23468132) {ECO:0000250|UniProtKB:P21440, ECO:0000269|PubMed:15258199, ECO:0000269|PubMed:19674157, ECO:0000269|PubMed:23468132}
Applications
WB, IHC-P
Dilution
WB--1:500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
795793688982039366571175231622346813224806754247234702459463521820390234681322404584093665712801225821820390
Molecular Weight
141523
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=5244
Uniprot URL
https://www.uniprot.org/uniprot/P21439
Available Sizes
Frequently Asked Questions
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