VLDLR Antibody (Center) [APR07213G]

Product Specifications

Background

Tissue Location: Abundant in heart and skeletal muscle; also ovary and kidney; not in liver

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality VLDLR Antibody (Center) [APR07213G].

Synonyms

Very low-density lipoprotein receptor, VLDL receptor, VLDL-R, VLDLR

Gene Name

VLDLR

Gene ID

7436

UniProt

P98155

Chromosomal Location

Membrane; Single-pass type I membrane protein. Membrane, clathrin-coated pit; Single-pass type I membrane protein

Applications

WB, IHC-P, FC

Dilution

IHC-P--1:100~500 WB--1:2000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation (By similarity) .