PTPLB Antibody (C-term) [AMR09654G]
Product Specifications
Background
Tissue Location: Highly expressed in testis, spleen, prostate, colon and heart, followed by moderate expression in thymus, ovary, small intestine, peripheral blood leukocytes, liver, skeletal muscle and pancreas. Weakly detected in kidney, placenta, brain and lung
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PTPLB Antibody (C-term) [AMR09654G].
Synonyms
Very-long-chain (3R) -3-hydroxyacyl-CoA dehydratase 2, 3-hydroxyacyl-CoA dehydratase 2, HACD2, Protein-tyrosine phosphatase-like member B, PTPLB, HACD2
Gene Name
HACD2 {ECO:0000303|PubMed:18554506, ECO:0000312|HGNC:HGNC:9640}
Gene ID
201562
UniProt
Q6Y1H2
Chromosomal Location
Endoplasmic reticulum membrane; Multi-pass membrane protein
Applications
IHC-P, FC, WB
Dilution
WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Catalyzes the third of the very long-chain fatty acids (VLCFA) elongation four-step cycle (condensation, reduction, dehydration, and reduction) . This endoplasmic reticulum-elongation process is characterized by the addition of two carbons to the lipid chain through each cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of elongation. Therefore, it participates in the production of various VLCFAs involved in multiple biological processes as precursors of membrane lipids and lipid mediators.
Molecular Weight
28368
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=201562
Uniprot URL
https://www.uniprot.org/uniprot/Q6Y1H2
Available Sizes
Frequently Asked Questions
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