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PTPLB Antibody (C-term) [AMR09654G]

Product Specifications

Background

Tissue Location: Highly expressed in testis, spleen, prostate, colon and heart, followed by moderate expression in thymus, ovary, small intestine, peripheral blood leukocytes, liver, skeletal muscle and pancreas. Weakly detected in kidney, placenta, brain and lung

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PTPLB Antibody (C-term) [AMR09654G].

Synonyms

Very-long-chain (3R) -3-hydroxyacyl-CoA dehydratase 2, 3-hydroxyacyl-CoA dehydratase 2, HACD2, Protein-tyrosine phosphatase-like member B, PTPLB, HACD2

Gene Name

HACD2 {ECO:0000303|PubMed:18554506, ECO:0000312|HGNC:HGNC:9640}

Gene ID

201562

UniProt

Q6Y1H2

Chromosomal Location

Endoplasmic reticulum membrane; Multi-pass membrane protein

Applications

IHC-P, FC, WB

Dilution

WB--1:1000 IHC-P--1:100~500 FC--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Catalyzes the third of the very long-chain fatty acids (VLCFA) elongation four-step cycle (condensation, reduction, dehydration, and reduction) . This endoplasmic reticulum-elongation process is characterized by the addition of two carbons to the lipid chain through each cycle. This enzyme catalyzes the dehydration of the 3-hydroxyacyl-CoA intermediate into trans-2,3-enoyl-CoA, within each cycle of elongation. Therefore, it participates in the production of various VLCFAs involved in multiple biological processes as precursors of membrane lipids and lipid mediators.

Molecular Weight

28368

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=201562

Uniprot URL

https://www.uniprot.org/uniprot/Q6Y1H2

Available Sizes

Frequently Asked Questions

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