RXRA Antibody (Center) [AMR09792G]
Product Specifications
Background
Tissue Location: Expressed in lung fibroblasts (at protein level) (PubMed:30216632) . Expressed in monocytes (PubMed:26463675) . Highly expressed in liver, also found in kidney and brain (PubMed:24275569, PubMed:2159111, PubMed:14702039) .
Synonyms
Retinoic acid receptor RXR-alpha, Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha, RXRA, NR2B1
Gene Name
RXRA
Gene ID
6256
UniProt
P19793
Chromosomal Location
Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407, ECO:0000269|PubMed:11915042, ECO:0000269|PubMed:12145331, ECO:0000269|PubMed:15509776, ECO:0000269|PubMed:17761950, ECO:0000269|PubMed:28167758}. Cytoplasm. Mitochondrion. Note=Localization to the nucleus is enhanced by vitamin D3 (PubMed:15509776) . Nuclear localization may be enhanced by the interaction with heterodimerization partner VDR (PubMed:12145331) . Translocation to the mitochondrion upon interaction with NR4A1 (PubMed:17761950, PubMed:15509776) . Increased nuclear localization upon pulsatile shear stress (PubMed:28167758)
Applications
WB, IHC-P
Dilution
WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
11162439119150421019569011162439119150422816775817761950161071411880076719167885101956901116243911915042177619502816775813102602021556620215566926703610195690119150422816775829021580290215801019569028167758281677581214533115509776264636752541764930216632
Molecular Weight
50811
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RXRA Antibody (Center) [AMR09792G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6256
Uniprot URL
https://www.uniprot.org/uniprot/P19793
Available Sizes
Curated Selection
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