RXRA Antibody (Center) [AMR09792G]

Product Specifications

Background

Tissue Location: Expressed in lung fibroblasts (at protein level) (PubMed:30216632) . Expressed in monocytes (PubMed:26463675) . Highly expressed in liver, also found in kidney and brain (PubMed:24275569, PubMed:2159111, PubMed:14702039) .

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RXRA Antibody (Center) [AMR09792G].

Synonyms

Retinoic acid receptor RXR-alpha, Nuclear receptor subfamily 2 group B member 1, Retinoid X receptor alpha, RXRA, NR2B1

Gene Name

RXRA

Gene ID

6256

UniProt

P19793

Chromosomal Location

Nucleus {ECO:0000255|PROSITE-ProRule:PRU00407, ECO:0000269|PubMed:11915042, ECO:0000269|PubMed:12145331, ECO:0000269|PubMed:15509776, ECO:0000269|PubMed:17761950, ECO:0000269|PubMed:28167758}. Cytoplasm. Mitochondrion. Note=Localization to the nucleus is enhanced by vitamin D3 (PubMed:15509776) . Nuclear localization may be enhanced by the interaction with heterodimerization partner VDR (PubMed:12145331) . Translocation to the mitochondrion upon interaction with NR4A1 (PubMed:17761950, PubMed:15509776) . Increased nuclear localization upon pulsatile shear stress (PubMed:28167758)

Applications

WB, IHC-P

Dilution

WB--1:1000 IHC-P--1:100~500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

11162439119150421019569011162439119150422816775817761950161071411880076719167885101956901116243911915042177619502816775813102602021556620215566926703610195690119150422816775829021580290215801019569028167758281677581214533115509776264636752541764930216632