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Phospho-ENT1 (Slc29a1) (S254) Antibody [AMM07126G]

Product Specifications

Background

Tissue Location: Detected in erythrocytes (at protein level) . Expressed in heart, brain, mammary gland, erythrocytes and placenta, and also in fetal liver and spleen.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality Phospho-ENT1 (Slc29a1) (S254) Antibody [AMM07126G].

Synonyms

Equilibrative nucleoside transporter 1, Equilibrative nitrobenzylmercaptopurine riboside-sensitive nucleoside transporter, Equilibrative NBMPR-sensitive nucleoside transporter, Nucleoside transporter, es-type, Solute carrier family 29 member 1, SLC29A1, ENT1

Gene Name

SLC29A1

Gene ID

2030

UniProt

Q99808

Chromosomal Location

Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Predominantly localized in the basolateral membrane in polarized MDCK cells

Applications

DB

Dilution

DB--1:500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by two-step phosphospecific peptide affinity purification.

Function

Mediates both influx and efflux of nucleosides across the membrane (equilibrative transporter) . It is sensitive (ES) to low concentrations of the inhibitor nitrobenzylmercaptopurine riboside (NBMPR) and is sodium-independent. It has a higher affinity for adenosine. Inhibited by dipyridamole and dilazep (anticancer chemotherapeutics drugs) .

Molecular Weight

50219

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=2030

Uniprot URL

https://www.uniprot.org/uniprot/Q99808

Available Sizes

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