SMPD2 Antibody (N-term) [APR13414G]

Product Specifications

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SMPD2 Antibody (N-term) [APR13414G].

Synonyms

Sphingomyelin phosphodiesterase 2, Lyso-platelet-activating factor-phospholipase C, Lyso-PAF-PLC, Neutral sphingomyelinase, N-SMase, nSMase, SMPD2

Gene Name

HGNC:11121

Gene ID

6610

UniProt

O60906

Chromosomal Location

Membrane; Multi-pass membrane protein.

Applications

WB, FC

Dilution

WB--1:1000 FC--1:10~50

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Function

Catalyzes the hydrolysis of sphingomyelin to form ceramide and phosphocholine. Ceramide mediates numerous cellular functions, such as apoptosis and growth arrest, and is capable of regulating these 2 cellular events independently. Also hydrolyzes sphingosylphosphocholine. Hydrolyze 1-acyl-2-lyso-sn-glycero-3- phosphocholine (lyso-PC) and 1-O-alkyl-2-lyso-sn-glycero-3- phosphocholine (lyso-platelet-activating factor) .