ARFGAP1 Antibody (C-term) [APR14277G]
Product Specifications
Synonyms
ADP-ribosylation factor GTPase-activating protein 1, ARF GAP 1, ADP-ribosylation factor 1 GTPase-activating protein, ARF1 GAP, ARF1-directed GTPase-activating protein, ARFGAP1, ARF1GAP
Gene Name
ARFGAP1
Gene ID
55738
UniProt
Q8N6T3
Chromosomal Location
Cytoplasm. Golgi apparatus. Note=Associates with the Golgi complex.
Applications
WB, IHC-P
Dilution
WB--1:8000 WB--1:1000 IHC-P--1:100~500
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
GTPase-activating protein (GAP) for the ADP ribosylation factor 1 (ARF1) . Involved in membrane trafficking and /or vesicle transport. Promotes hydrolysis of the ARF1-bound GTP and thus, is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles, a prerequisite for vesicle's fusion with target compartment. Probably regulates ARF1-mediated transport via its interaction with the KDELR proteins and TMED2. Overexpression induces the redistribution of the entire Golgi complex to the endoplasmic reticulum, as when ARF1 is deactivated. Its activity is stimulated by phosphoinosides and inhibited by phosphatidylcholine (By similarity) .
Molecular Weight
44668
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ARFGAP1 Antibody (C-term) [APR14277G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=55738
Uniprot URL
https://www.uniprot.org/uniprot/Q8N6T3
Available Sizes
Curated Selection
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