TRPC6 rabbit pAb
The protein encoded by this gene forms a receptor-activated calcium channel in the cell membrane. The channel is activated by diacylglycerol and is thought to be under the control of a phosphatidylinositol second messenger system. Activation of this channel occurs independently of protein kinase C and is not triggered by low levels of intracellular calcium. Defects in this gene are a cause of focal segmental glomerulosclerosis 2 (FSGS2). [provided by RefSeq, Mar 2009],
Product Specifications
Background
Gene ID
7225
UniProt
Q9Y210
Cellular Locus
Cell membrane ; Multi-pass membrane protein.
Host
Rabbit
Species Reactivity
Human,Mouse
Reactivity
Human; Mouse
Immunogen
Synthesized peptide derived from human TRPC6 AA range: 412-462
Clonality
Polyclonal
Isotype
IgG
Source
Rabbit
Applications
WB
Validated Applications
WB
Stability
-20°C/1 year
Concentration
1 mg/mL
Dilution
WB 1: 500-2000
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.
Product Datasheet
https://www.elkbiotech.com/upload/file/Antibodies/pAb/ES12548-1.pdf
Subcellular Location
Cell membrane ; Multi-pass membrane protein .
Gene ID (Human)
7225
SwissProt (Human)
Q9Y210
Available Sizes
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