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GABBR1 Antibody (N-Term) [APG03311G]

Product Specifications

Background

Tissue Location: Highly expressed in brain (PubMed:9844003, PubMed:9753614, PubMed:9872744) . Weakly expressed in heart, small intestine and uterus. Isoform 1A: Mainly expressed in granular cell and molecular layer (PubMed:9844003) . Isoform 1B: Mainly expressed in Purkinje cells (PubMed:9844003) . Isoform 1E: Predominantly expressed in peripheral tissues as kidney, lung, trachea, colon, small intestine, stomach, bone marrow, thymus and mammary gland (PubMed:10906333)

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GABBR1 Antibody (N-Term) [APG03311G].

Synonyms

Gamma-aminobutyric acid type B receptor subunit 1, GABA-B receptor 1, GABA-B-R1, GABA-BR1, GABABR1, Gb1, GABBR1, GPRC3A

Gene Name

GABBR1

Gene ID

2550

UniProt

Q9UBS5

Chromosomal Location

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane {ECO:0000250|UniProtKB:Q9Z0U4}; Multi-pass membrane protein. Cell projection, dendrite {ECO:0000250|UniProtKB:Q9Z0U4}. Note=Colocalizes with ATF4 in hippocampal neuron dendritic membranes (By similarity) . Coexpression of GABBR1 and GABBR2 is required for GABBR1 maturation and transport to the plasma membrane (PubMed:15617512) . {ECO:0000250|UniProtKB:Q9Z0U4, ECO:0000269|PubMed:15617512}

Applications

WB

Dilution

WB--1:2000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

98723169872744156175121816568822660477243050541816568810906333107730161007564498727442430505410075644984400398440039872316100756449872744226604779844003987231624305054

Molecular Weight

108320

Storage Conditions

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=2550

Uniprot URL

https://www.uniprot.org/uniprot/Q9UBS5

Available Sizes

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