SHH Antibody (C-term) [APR17859G]
Product Specifications
Synonyms
Sonic hedgehog protein, SHH, HHG-1, Sonic hedgehog protein N-product, Sonic hedgehog protein C-product, SHH
Gene Name
HGNC:10848
Gene ID
6469
UniProt
Q15465
Chromosomal Location
Endoplasmic reticulum membrane. Golgi apparatus membrane. Note=Co-localizes with HHAT in the ER and Golgi membrane.
Applications
WB
Dilution
WB--1:1000
Function
[Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity (By similarity) . Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN (By similarity) . Both activities occur in the reticulum endoplasmic (By similarity) . Once cleaved, ShhC is degraded in the endoplasmic reticulum (By similarity) .
Molecular Weight
49607
Storage Conditions
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SHH Antibody (C-term) [APR17859G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6469
Uniprot URL
https://www.uniprot.org/uniprot/Q15465
Available Sizes
Curated Selection
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