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BMPR1B Antibody (N-term K15) [APR15157G]

Product Specifications

Synonyms

Bone morphogenetic protein receptor type-1B, BMP type-1B receptor, BMPR-1B, CDw293, BMPR1B

Gene Name

BMPR1B

Gene ID

658

UniProt

O00238

Chromosomal Location

Cell membrane {ECO:0000250|UniProtKB:P36898}. Membrane; Single-pass type I membrane protein

Applications

WB

Dilution

WB--1:1000

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Function

On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP7/OP-1 and GDF5. Positively regulates chondrocyte differentiation through GDF5 interaction.

Molecular Weight

56930

Storage Conditions

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BMPR1B Antibody (N-term K15) [APR15157G].

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=658

Uniprot URL

https://www.uniprot.org/uniprot/O00238

Available Sizes

Curated Selection

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