BMPR1A Antibody (N-term) [AMM04377G]
Product Specifications
Background
Tissue Location: Highly expressed in skeletal muscle.
Synonyms
Bone morphogenetic protein receptor type-1A, BMP type-1A receptor, BMPR-1A, Activin receptor-like kinase 3, ALK-3, Serine/threonine-protein kinase receptor R5, SKR5, CD292, BMPR1A, ACVRLK3, ALK3
Gene Name
BMPR1A
Gene ID
657
UniProt
P36894
Chromosomal Location
Cell membrane {ECO:0000250|UniProtKB:P36898}; Single-pass type I membrane protein. Cell surface {ECO:0000250|UniProtKB:P36895}
Applications
FC, WB
Dilution
WB--1:1000 FC--1:10~50
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Function
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP2, BMP4, GDF5 and GDF6. Positively regulates chondrocyte differentiation through GDF5 interaction. Mediates induction of adipogenesis by GDF6.
Molecular Weight
60198
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BMPR1A Antibody (N-term) [AMM04377G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=657
Uniprot URL
https://www.uniprot.org/uniprot/P36894
Available Sizes
Curated Selection
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