SCNN1B Antibody (Center) [AMR09830G]
Product Specifications
Background
Tissue Location: Detected in placenta, lung and kidney (PubMed:7762608) . Expressed in kidney (at protein level) (PubMed:22207244) .
Synonyms
Amiloride-sensitive sodium channel subunit beta, Beta-NaCH, Epithelial Na (+) channel subunit beta, Beta-ENaC, ENaCB, Nonvoltage-gated sodium channel 1 subunit beta, SCNEB, SCNN1B
Gene Name
SCNN1B
Gene ID
6338
UniProt
P51168
Chromosomal Location
Apical cell membrane; Multi-pass membrane protein {ECO:0000250|UniProtKB:P37089}. Cytoplasmic vesicle membrane {ECO:0000250|UniProtKB:P37090}. Note=Apical membrane of epithelial cells.
Applications
WB
Dilution
WB--1:1000
Form
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Function
Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Plays an essential role in electrolyte and blood pressure homeostasis, but also in airway surface liquid homeostasis, which is important for proper clearance of mucus. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.
Molecular Weight
72659
Storage Conditions
Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Overview
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SCNN1B Antibody (Center) [AMR09830G].
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/?term=6338
Uniprot URL
https://www.uniprot.org/uniprot/P51168
Available Sizes
Curated Selection
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