ELOVL3 Antibody (C-term) [APR07676G]

Product Specifications

Background

Tissue Location: Testis..

Overview

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ELOVL3 Antibody (C-term) [APR07676G].

Synonyms

Elongation of very long chain fatty acids protein 3, 3-keto acyl-CoA synthase ELOVL3, Cold-inducible glycoprotein of 30 kDa, ELOVL fatty acid elongase 3, ELOVL FA elongase 3, Very-long-chain 3-oxoacyl-CoA synthase 3, ELOVL3, CIG30

Gene Name

ELOVL3 {ECO:0000255|HAMAP-Rule:MF_03203}

Gene ID

83401

UniProt

Q9HB03

Chromosomal Location

Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03203, ECO:0000269|PubMed:20937905}; Multi- pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03203}

Applications

Dilution

WB--1:500

Form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Function

Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and unsaturated acyl-CoA substrates with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate in the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators.